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Pheromones: Potential Participants in Your Sex Life
By Deb Levine, MA
WebMD Feature
You've never heard of pheromones? Well, it's time to learn about the part they play in your sex life, because it could be substantial. The concept of a human pheromone, or sexual scent of attraction, has been debated and researched for years.
In most animals, the relationship between pheromones and mating is straightforward. Sea urchins, for example, release pheromones into the surrounding water, sending a chemical message that triggers other urchins in the colony to eject their sex cells simultaneously.
Human pheromones, on the other hand, are highly individualized, and not always noticeable. In 1986 Dr. Winifred Cutler, a biologist and behavioral endocrinologist, codiscovered pheromones in our underarms. She and her team of researchers found that once any overbearing underarm sweat was removed, what remained were the odorless materials containing the pheromones.
Dr. Cutler's original studies in the '70s showed that women who have regular sex with men have more regular menstrual cycles than women who have sporadic sex. Regular sex delayed the decline of estrogen and made women more fertile. This led the research team to look for what the man was providing in the equation. By 1986 they realized it was pheromones.
Menstrual Synchronization
There's more on how pheromones affect women's menstrual cycles. Think back to college, or to growing up if you had sisters. Most women who live with or near other women adjust their menstrual cycle timing to each other. A recent study at the University of Chicago by Martha McClintock exposed a group of women to a whiff of perspiration from other women. It caused their menstrual cycles to speed up or slow down depending on the time in the month the sweat was collected -- before, during or after ovulation. This was the first proof that people produce and respond to pheromones.
By Deb Levine, MA
WebMD Feature
You've never heard of pheromones? Well, it's time to learn about the part they play in your sex life, because it could be substantial. The concept of a human pheromone, or sexual scent of attraction, has been debated and researched for years.
In most animals, the relationship between pheromones and mating is straightforward. Sea urchins, for example, release pheromones into the surrounding water, sending a chemical message that triggers other urchins in the colony to eject their sex cells simultaneously.
Human pheromones, on the other hand, are highly individualized, and not always noticeable. In 1986 Dr. Winifred Cutler, a biologist and behavioral endocrinologist, codiscovered pheromones in our underarms. She and her team of researchers found that once any overbearing underarm sweat was removed, what remained were the odorless materials containing the pheromones.
Dr. Cutler's original studies in the '70s showed that women who have regular sex with men have more regular menstrual cycles than women who have sporadic sex. Regular sex delayed the decline of estrogen and made women more fertile. This led the research team to look for what the man was providing in the equation. By 1986 they realized it was pheromones.
Menstrual Synchronization
There's more on how pheromones affect women's menstrual cycles. Think back to college, or to growing up if you had sisters. Most women who live with or near other women adjust their menstrual cycle timing to each other. A recent study at the University of Chicago by Martha McClintock exposed a group of women to a whiff of perspiration from other women. It caused their menstrual cycles to speed up or slow down depending on the time in the month the sweat was collected -- before, during or after ovulation. This was the first proof that people produce and respond to pheromones.
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Sex Organ Up Your Nose
Transcript & real audio of Karl Kruszelnicki's Great Moments in Science program. Sex Organ Up Your Nose
By Karl S. Kruszelnicki
We humans have a bunch of highly-developed senses, but most of our communication happens with sound and vision. Not much communication between people happens with smell. But now we are beginning to prove that we humans can influence each other with our smells — and, that we pick up these smells with a strange sex organ inside our noses!
The anatomy scientists have known for a long time about the 'olfactory epithelium'. Olfactory means 'related to smell'. The olfactory epithelium is a patch of yellowish tissue high up in 'ceiling' of the nose. Normally, it is poorly ventilated, but when we sniff deeply, we pass lots of air over it. In this yellow patch, there are sensory cells specially adapted for smelling. Chemicals in the air enter the nose, excite the sensory cells, and then we get the sensation of smell.
There is also another area in the human nose that we can detect odours with — but until recently, most scientists didn't believe it existed! This is the VNO, which stands for 'vomeronasal organ'. Fishes, birds, and some mammals don't have a VNO, but it is very well developed in snakes and lizards.
It was first discovered by the Dutch anatomist, Ruysch, way back in 1703. It's right next to the wall that separates the nostrils, on the 'floor' of the nose, and about a centimetre inside the nose. There's one in each nostril. It looks like a hollow tube, with only a very small opening (about one tenth of a millimetre across) into the nose. Each VNO is very small, and hard to see.
This might be why the vomeronasal organ fell out of favour, and soon the anatomists didn't even believe it existed. By the 1930's, physiologists said that not only did we humans definitely not have a VNO, but there was no structure in the brain to process the information from any such organ. However, in 1991, a careful study found that 910 out of 1,000 people had an easily-found VNO. But the fact that we humans have a vomeronasal organ, does not mean that it does anything.
In 1994, Luis Monti-Bloch and his team from the University of Utah actually managed to thread very fine insulated electrical wires into the VNOs of volunteers. They then wafted various smells up the noses of their volunteers, and looked for electrical activity in the cells of the VNO. These smells were various odourless chemicals from the skin of men and women. The volunteers had absolutely no conscious idea that they were getting these smells — in other words, their olfactory epithelium which smells perfumes and pollutants, did not trigger. The cells in the males' VNOs fired when they got female skin smells, and female VNOs responded to male skin smells. But the VNOs did not respond to skin smells from the same sex.
It was odd that the volunteers didn't consciously realise that their VNOs were being stimulated. We can waft a smell up their nose, and their VNO can fire frantically with electrical activity — but all the volunteer gets is a vague, generalised emotion of feeling fine.
But in early 1998, an excellent experiment showed a more definite effect — that some female smells could trigger women's menstrual cycles. Kathleen Stern and Martha McClintock from the Psychology Department at the University of Chicago did the experiment. They had some 'donor' women, who gave away the smells in their armpits (via a pad that they wore for 8 hours per day). They also had some 'recipient' women, who were exposed to these smells. The smells were completely odourless, as far their conscious brains were concerned. And of course, the two groups, donors and recipients, never met face-to-face.
The smells were taken from the donor women at two different times in their menstrual cycle. When the smells were taken before the donors ovulated, the recipients' menstrual cycles became shorter. But when the smells were taken right on the donors' ovulation, the recipients' menstrual cycles became longer. The overall effect was to synchronise the cycle of the recipient, with the cycle of the donor.
This was a pretty good experiment, but we're still not 100 per cent sure that the smells from one human can influence another human. For one thing, this effect happened to only 70 per cent of the volunteers — so what's going on in the remaining 30 per cent? For another thing, our neuroanatomists have not yet proved that nerves from the human VNO go to the relevant parts of the brain. The only way to do that is to get several corpses, add some dye to the VNO, and wait a few month for the dye to migrate, and then very carefully cut open the brain.
So if your boyfriend or girlfriend gets up your nose, it may not be their fault.
This Great Moment in Science was originally published in 1998.
Transcript & real audio of Karl Kruszelnicki's Great Moments in Science program. Sex Organ Up Your Nose
By Karl S. Kruszelnicki
We humans have a bunch of highly-developed senses, but most of our communication happens with sound and vision. Not much communication between people happens with smell. But now we are beginning to prove that we humans can influence each other with our smells — and, that we pick up these smells with a strange sex organ inside our noses!
The anatomy scientists have known for a long time about the 'olfactory epithelium'. Olfactory means 'related to smell'. The olfactory epithelium is a patch of yellowish tissue high up in 'ceiling' of the nose. Normally, it is poorly ventilated, but when we sniff deeply, we pass lots of air over it. In this yellow patch, there are sensory cells specially adapted for smelling. Chemicals in the air enter the nose, excite the sensory cells, and then we get the sensation of smell.
There is also another area in the human nose that we can detect odours with — but until recently, most scientists didn't believe it existed! This is the VNO, which stands for 'vomeronasal organ'. Fishes, birds, and some mammals don't have a VNO, but it is very well developed in snakes and lizards.
It was first discovered by the Dutch anatomist, Ruysch, way back in 1703. It's right next to the wall that separates the nostrils, on the 'floor' of the nose, and about a centimetre inside the nose. There's one in each nostril. It looks like a hollow tube, with only a very small opening (about one tenth of a millimetre across) into the nose. Each VNO is very small, and hard to see.
This might be why the vomeronasal organ fell out of favour, and soon the anatomists didn't even believe it existed. By the 1930's, physiologists said that not only did we humans definitely not have a VNO, but there was no structure in the brain to process the information from any such organ. However, in 1991, a careful study found that 910 out of 1,000 people had an easily-found VNO. But the fact that we humans have a vomeronasal organ, does not mean that it does anything.
In 1994, Luis Monti-Bloch and his team from the University of Utah actually managed to thread very fine insulated electrical wires into the VNOs of volunteers. They then wafted various smells up the noses of their volunteers, and looked for electrical activity in the cells of the VNO. These smells were various odourless chemicals from the skin of men and women. The volunteers had absolutely no conscious idea that they were getting these smells — in other words, their olfactory epithelium which smells perfumes and pollutants, did not trigger. The cells in the males' VNOs fired when they got female skin smells, and female VNOs responded to male skin smells. But the VNOs did not respond to skin smells from the same sex.
It was odd that the volunteers didn't consciously realise that their VNOs were being stimulated. We can waft a smell up their nose, and their VNO can fire frantically with electrical activity — but all the volunteer gets is a vague, generalised emotion of feeling fine.
But in early 1998, an excellent experiment showed a more definite effect — that some female smells could trigger women's menstrual cycles. Kathleen Stern and Martha McClintock from the Psychology Department at the University of Chicago did the experiment. They had some 'donor' women, who gave away the smells in their armpits (via a pad that they wore for 8 hours per day). They also had some 'recipient' women, who were exposed to these smells. The smells were completely odourless, as far their conscious brains were concerned. And of course, the two groups, donors and recipients, never met face-to-face.
The smells were taken from the donor women at two different times in their menstrual cycle. When the smells were taken before the donors ovulated, the recipients' menstrual cycles became shorter. But when the smells were taken right on the donors' ovulation, the recipients' menstrual cycles became longer. The overall effect was to synchronise the cycle of the recipient, with the cycle of the donor.
This was a pretty good experiment, but we're still not 100 per cent sure that the smells from one human can influence another human. For one thing, this effect happened to only 70 per cent of the volunteers — so what's going on in the remaining 30 per cent? For another thing, our neuroanatomists have not yet proved that nerves from the human VNO go to the relevant parts of the brain. The only way to do that is to get several corpses, add some dye to the VNO, and wait a few month for the dye to migrate, and then very carefully cut open the brain.
So if your boyfriend or girlfriend gets up your nose, it may not be their fault.
This Great Moment in Science was originally published in 1998.
Study finds proof that humans react to pheromones Bees
Many animals use pheromones to communicate.
March 11, 1998
Web posted at: 8:59 p.m. EST (0159 GMT)
(CNN) -- The power of smell is undeniable, as the multi-billion dollar perfume industry testifies. But is it possible that humans are influenced by airborne chemicals undetectable as odors, called pheromones?
Though any number of animals and insects use pheromones to communicate with each other about important things such as food, territory and sex, the idea that humans might be similarly influenced has been controversial among scientists.
But now, researchers at the University of Chicago say they have the first proof that humans produce and react to pheromones.
In findings published in the journal Nature, researchers say they found that female ovulation can be regulated -- made longer or shorter -- through the use of pheromones.
"The pheromones regulate the time of ovulation. There are two pheromones -- one that makes ovulation more likely and the other that suppresses it and makes it less likely," said Martha McClintock of the University of Chicago.
There could be important practical implications from this finding. Because pheromones influence the release of eggs, researchers say they may provide a more natural way of preventing pregnancy or treating infertility.
However, researchers say more study is needed to find out if there are other types of pheromones and if they are as powerful in humans as they are in other species.
One enduring mystery of pheromones is that if they are undetectable by the human sense of smell, how can humans be influenced by them?
The answer, some researchers believe, is that pheromones are detected by the same nerve cells in the nose used to detect odor or perhaps by another structure in the nose called the vomeronasal organ.
Medical Correspondent Rhonda Rowland contributed to this report.
Many animals use pheromones to communicate.
March 11, 1998
Web posted at: 8:59 p.m. EST (0159 GMT)
(CNN) -- The power of smell is undeniable, as the multi-billion dollar perfume industry testifies. But is it possible that humans are influenced by airborne chemicals undetectable as odors, called pheromones?
Though any number of animals and insects use pheromones to communicate with each other about important things such as food, territory and sex, the idea that humans might be similarly influenced has been controversial among scientists.
But now, researchers at the University of Chicago say they have the first proof that humans produce and react to pheromones.
In findings published in the journal Nature, researchers say they found that female ovulation can be regulated -- made longer or shorter -- through the use of pheromones.
"The pheromones regulate the time of ovulation. There are two pheromones -- one that makes ovulation more likely and the other that suppresses it and makes it less likely," said Martha McClintock of the University of Chicago.
There could be important practical implications from this finding. Because pheromones influence the release of eggs, researchers say they may provide a more natural way of preventing pregnancy or treating infertility.
However, researchers say more study is needed to find out if there are other types of pheromones and if they are as powerful in humans as they are in other species.
One enduring mystery of pheromones is that if they are undetectable by the human sense of smell, how can humans be influenced by them?
The answer, some researchers believe, is that pheromones are detected by the same nerve cells in the nose used to detect odor or perhaps by another structure in the nose called the vomeronasal organ.
Medical Correspondent Rhonda Rowland contributed to this report.
Humans naturally produce the pheromone scent which is released from the sweat glands. It is has been natures way for men and women to signal attraction at the primal and genetic level. It has been proven that pheromones can effect ovulation cycles in women. Evolution of the human species and the advanced development of our brain has reduced our dependence on natural biological signals and excretions to induce mating. Humans understand the pleasures and purpose of intimate activity and have adapted to rely less on these biological assistants. Though we now produce only minimal amounts of our own pheromones, they still can trigger nature's original primal scent. We still respond to this signal. We all naturally produce this in different quantities. Some of us produce more than others. We are all different. When we shower daily to remove unacceptable body odor, we also remove these pheromones which are released by our sweat glands. In essence, it renders us genetically invisible to others. And, when you use a nice smelling cologne or deodorant you are only covering up your own natural pheromones. This pheromone, called 5-Alpha-Androst-16-En-3-One, has been identified as a proven human pheromone. It can now be synthesized by chemists in a laboratory. 98% Pure, 5-Alpha-Androst-16-En-3-One has a very distinct odor, the musky, pungent, component in your body sweat. All indications demonstrate that the .01 to .015 percentages (by weight), when veiled by a minimal fragrance additive, balanced to not mask the scent of the pheromone, are the most effective.
Androstenone
(5alpha-androst-16-en-3-one)
(5alpha-androst-16-en-3-one)
Alpha - Androstenol
(5alpha-androst-16-en-3alpha-ol)
(5alpha-androst-16-en-3alpha-ol)
Our pheromones are experimental-grade human pheromones, Alpha-Androstenol
The alpha isomer of Androstenol makes the wearer seem less intimidating and more approachable. People just get comfortable with you.
Alpha-Androstenol is produced by both men and women and does have significant affects on both sexes.
In a test at the University Of Warwick, Androstenol exposed men and women both rated women as sexier, warmer, and more attractive than when they were not exposed to Alpha-Androstenol. However, women also rated men wearing Alpha-Androstenol consistently higher on the attractiveness scale while men consistently downgraded other men wearing Androstenol.
Women who are exposed to Alpha-Androstenol tend to initiate social contact with males, and are more likely to be friendly and receptive to males initiating contact with them. Androstenol does cause talkativeness in females, sometimes to the extreme.
Alpha-Androstenol has a musky sweaty aromatic scent. Some say that it smells very much like sandalwood.
Alpha-Androstenol is produced by both men and women and does have significant affects on both sexes.
In a test at the University Of Warwick, Androstenol exposed men and women both rated women as sexier, warmer, and more attractive than when they were not exposed to Alpha-Androstenol. However, women also rated men wearing Alpha-Androstenol consistently higher on the attractiveness scale while men consistently downgraded other men wearing Androstenol.
Women who are exposed to Alpha-Androstenol tend to initiate social contact with males, and are more likely to be friendly and receptive to males initiating contact with them. Androstenol does cause talkativeness in females, sometimes to the extreme.
Alpha-Androstenol has a musky sweaty aromatic scent. Some say that it smells very much like sandalwood.
Androstadienone
(delta 4, 16-androstadien-3-one)
(delta 4, 16-androstadien-3-one)
This is a pheromone that is widely documented to have a very specific effect on the brain activity of women. One particular study has shown that it affects attention and social cognition areas of the brain. It is also one of the only pheromones that has been shown to stimulate the VNO, and so has been described as a vomeropherin.
Androstadienone, more commonly known as A1, is a very popular pheromone within the pheromone community. One of it’s more remarkable effects is that it can elevate a woman’s mood, and even alleviate PMS stress! It has been known to increase intimacy and comfort, and can also increase caring feelings. It has been called the “love pheromone” because of the nature of the feelings and reactions it induces in women, and also because of it’s usefulness in more cozy relationship situations.
Androstadienone, more commonly known as A1, is a very popular pheromone within the pheromone community. One of it’s more remarkable effects is that it can elevate a woman’s mood, and even alleviate PMS stress! It has been known to increase intimacy and comfort, and can also increase caring feelings. It has been called the “love pheromone” because of the nature of the feelings and reactions it induces in women, and also because of it’s usefulness in more cozy relationship situations.
Note : Article In English To Preserve Originality
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